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SPECTRA
IMDx™

Gastric Cancer

Gastric cancer is one of the most common cancer worldwidewith over 1 million new cases in 2018. In Asia, gastric cancer is the secondleading cause of cancer mortality.


While early gastric cancer diagnosis improves prognosis*, early diagnosis has always been a challenge to physicians worldwide.

*5 years survival >90%

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Normal tissue

Current Practice

White-light endoscopy is the most common method for visuallydiagnosing early signs of gastric cancer in hospitals. Images of the stomachlining are displayed on the system monitor to guide thedoctors on the best sites to take biopsies. The biopsies will confirm the diagnosis after a few days.


The delay in diagnosis is because conventional white light endoscopy cannotaccurately differentiate normal vs cancerous tissues.

82%

48%

Sensitivity

Cancer   VS   Non-Cancer
SPECTRA IMDx™ enables in-vivo moleculardiagnosis for early gastric cancer. Using Raman Spectroscopy, the system provides objective, real-timefeedback for physicians to determine probability of the patient having gastric cancer, leading to improvedearly gastric cancer diagnosis.

The system classifies high grade dysplasia and gastric cancer as high risk and gastritis, intestinal metaplasia, and low grade dysplasia as low risk. High risk lesions are generally treated with resection while low risk lesions can be closely followed up.

SPECTRA IMDx™   

White Light

87.3%

67%

Real-time Feedback
Immediate feedback on cancer risk to support physician's diagnosis

67%

80%

Specificity

Sensitivity

About
Raman Spectroscopy

Raman Spectral Analysis is a technique capable of capturing molecular information associated with the cellular metabolic constituents when the tissue molecules are excited by light energy directed at the tissue.


With the technology, the system is able to help identify tissue with high probability of having gastric cancer.


AI-enabled
Objective Analysis
Using clinical data to distinguish molecular signatures of high risk gastric lesions

Compatibility with Endoscope
Miniaturized probe compatible with existing gastrointestinal endoscopes


Cancerous tissue


Above Images: Difficult to differentiate between normal tissue (left) and cancerous tissue (right) under conventional white light endoscopy.